The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 1996
Filed:
Dec. 21, 1994
Applicant:
Inventors:
Jean Ackermann, Basel, CH;
David Banner, Basel, CH;
Klaus Gubernator, Freiburg, DE;
Kurt Hilpert, Hofstetten, CH;
G erard Schmid, Kienberg, CH;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
5142362 ; 5142315 ; 5142355 ; 5142372 ; 5142378 ; 5142385 ; 514252 ; 514255 ; 514315 ; 514318 ; 514326 ; 514331 ; 514333 ; 544111 ; 544132 ; 544160 ; 544405 ; 544408 ; 544407 ; 546193 ; 546194 ; 546231 ; 546233 ; 546247 ;
Abstract
Sulfonamidocarboxamides of the formula ##STR1## wherein A, M, Q, X and Y have the significance given in the description, as well as hydrates, solvates and salts thereof, which inhibit thrombin-induced blood platelet aggregation and clotting of fibrinogen in plasma, as described. The compounds of formula I can be prepared by amidination of a cyclic amino group standing for grouping X or by C(O)N(Q) amide formation.