Location History:
- San Diego, CA (US) (2003)
- San Leandro, CA (US) (2003)
- San Lorenzo, CA (US) (2004)
Company Filing History:
Years Active: 2003-2004
Title: Kevin Patrick Keegan: Innovator in Tumor Suppressor Research
Introduction
Kevin Patrick Keegan is a notable inventor based in San Diego, CA. He has made significant contributions to the field of genetics, particularly in the study of tumor suppressor genes and proteins. With a total of 4 patents, his work has implications for both pest control and therapeutic development.
Latest Patents
One of his latest patents focuses on insect p53 tumor suppressor genes and proteins. This patent describes a family of p53 tumor suppressor nucleic acids and proteins isolated from various insect species. The p53 nucleic acid and protein can be utilized to genetically modify metazoan invertebrate organisms, such as insects and worms, or cultured cells. This modification results in p53 expression or mis-expression, which can be used in screening assays to identify candidate compounds that may serve as pesticidal agents or therapeutics interacting with the p53 protein. Additionally, the patent includes nucleic acid and protein sequences for Drosophila p33 and Rb tumor suppressors.
Another significant patent involves methods of screening for agents that modulate the interaction of human ECT2 polypeptide with an ECT2 binding target. This patent provides human Ect2 polypeptide, fragments, and derivatives, along with vectors and host cells for expression and production of Ect2 polypeptide. Various high-throughput methods for screening agents that modulate the interaction of Ect2 with an Ect2 binding agent are also included.
Career Highlights
Kevin Patrick Keegan is currently associated with Exelixis, Inc., where he continues to advance his research in genetics and tumor suppressor mechanisms. His work has garnered attention in the scientific community for its innovative approach to understanding and manipulating genetic functions.
Collaborations
Throughout his career, Kevin has collaborated with notable colleagues, including Thomas J Stout and Michael Martin Ollmann. These collaborations have further enriched his research and contributed to the development of his patents.
Conclusion
Kevin Patrick Keegan is a distinguished inventor whose work in tumor suppressor research has the potential to impact both agricultural and medical fields. His innovative patents reflect a commitment to advancing genetic research and its applications.