San Francisco, CA, United States of America

Keith R Yamamoto


Average Co-Inventor Count = 3.3

ph-index = 1

Forward Citations = 10(Granted Patents)


Company Filing History:


Years Active: 1989-2005

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4 patents (USPTO):

Title: Keith R Yamamoto: Innovator in Nuclear Receptor Research

Introduction

Keith R Yamamoto is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of nuclear receptor research, holding a total of 4 patents. His work focuses on methods for modulating nuclear receptor coactivator binding, which has implications for understanding various biological processes.

Latest Patents

One of his latest patents is titled "Methods for modulating nuclear receptor coactivator binding." This invention relates to methods and compounds for modulating the binding of coactivators to nuclear receptors. It includes a method for identifying residues that comprise a coactivator binding site for a nuclear receptor of interest. Additionally, it provides methods for identifying agonists and antagonists that bind to these sites. The invention exemplifies the identification and manipulation of the coactivator binding site of the thyroid receptor (TR) and extends to other nuclear receptors such as RAR, RXR, PPAR, VDR, ER, GR, PR, MR, and AR.

Another significant patent is "Transition in transcriptional activation by intracellular hormone." This patent reveals that intracellular hormone receptors undergo posttranslational regulation. It provides assays to assess cancer progression and facilitates the discovery of a new class of biologically active compounds, along with related kits.

Career Highlights

Throughout his career, Keith has worked with esteemed institutions, including the University of California and the United States of America as represented by the Department of Health. His research has contributed to advancements in understanding nuclear receptor functions and their implications in health and disease.

Collaborations

Keith has collaborated with notable colleagues such as John D Baxter and Beatrice Darimont. These collaborations have further enriched his research and innovation in the field.

Conclusion

Keith R Yamamoto is a distinguished inventor whose work in nuclear receptor research has led to valuable patents and advancements in the field. His contributions continue to influence scientific understanding and innovation.

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