Company Filing History:
Years Active: 1996-1999
Title: Innovations of Keith L. Frost
Introduction
Keith L. Frost is a notable inventor based in Seattle, WA, with a significant contribution to the field of optical measurement and cytology. He holds a total of nine patents, showcasing his expertise and innovative spirit in developing advanced technologies.
Latest Patents
Among his latest patents is a method and apparatus for alias-free measurement of optical transfer. This invention focuses on measuring the optical transfer function of an optical system that images a bar pattern. It employs a one-dimensional fast Fourier transform to process sampled image data from the bar pattern. The system model utilizes robust measurements of the period, duty cycle, and center of each stripe in the pattern. The invention estimates a signal alias-free optical transfer function from the plurality of one-dimensional frequency representations of the signal. Additionally, an idealized bar pattern synthesized from the measured parameters generates an ideal optical transfer function. The noise-reduced optical transfer function is estimated from the optical transfer function of the signal and that of the synthesized bar pattern.
Another significant patent is the cytological slide scoring apparatus. This invention detects areas of interest at low magnification, identifying possible abnormal cells or other cells of interest through image processing and statistical pattern recognition techniques. At high magnification, the areas identified at low magnification are re-examined. The information from both scans is collated to determine the slide's status—whether it is normal, abnormal, or contains an endocervical component. The invention also provides a method and apparatus to train object feature and slide feature classifiers, contributing to the development of an automated cytology system that can process training slides for feedback classifier development.
Career Highlights
Keith L. Frost is currently associated with Neopath, Inc., where he continues to innovate and develop technologies that enhance optical measurement and cytological analysis. His work has significantly impacted the field, leading to advancements in automated systems for medical diagnostics.
Collaborations
He has collaborated with notable coworkers, including Jon W. Hayenga and James A. Stephanick, contributing to the success of various projects and innovations.
Conclusion
Keith L. Frost's contributions to the fields of optical measurement and cytology through his patents and work at Neopath, Inc. highlight his role as a leading inventor. His innovative spirit continues to drive advancements in technology and medical diagnostics.
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