Keiro Shirotani

Title: Innovations of Keiro Shirotani

Introduction

Keiro Shirotani is a notable inventor based in Fukushima, Japan. He has made significant contributions to the field of glycan detection and central nervous system research. With a total of two patents to his name, Shirotani's work is focused on developing methods that enhance the detection and analysis of glycoproteins.

Latest Patents

Shirotani's latest patents include a glycoform detection method and a glycoform detection device. These inventions aim to provide a rapid and specific method for detecting particular glycan-isoforms through a streamlined process. The glycan-isoform detection method involves quantifying an immune complex formed by mixing a test sample with a sugar chain non-reducing terminal residue-binding lectin and an antibody that specifically binds to the protein moiety of the glycan-isoform. By comparing the amount of the immune complex from the test sample with a control sample, the presence or absence of the glycan-isoform of interest can be determined.

Another significant patent focuses on the enrichment and separation of spinal fluid glycoproteins. This invention aims to develop a method for selectively isolating glycoproteins derived from the central nervous system. The method utilizes a two-stage separation procedure to enrich proteins that occur in trace amounts in body fluids or central nervous system cells. This research is crucial for identifying markers for central nervous system diseases.

Career Highlights

Keiro Shirotani is affiliated with the National Institute of Advanced Industrial Science and Technology. His work at this institution has allowed him to explore innovative solutions in the field of glycoprotein research. His contributions have the potential to advance the understanding of various diseases related to the central nervous system.

Collaborations

Shirotani has collaborated with notable colleagues such as Hisashi Narimatsu and Atsushi Kuno. These collaborations have further enriched his research and contributed to the development of his patents.

Conclusion

Keiro Shirotani's innovative work in glycan detection and central nervous system research highlights his significant contributions to science and technology. His patents reflect a commitment to advancing medical research and improving diagnostic methods.