Keiji Nishida

Title: Keiji Nishida: Innovator in Genome Editing

Introduction

Keiji Nishida is a prominent inventor based in Kobe, Japan, known for his significant contributions to the field of genome editing. With a total of eight patents to his name, Nishida has made remarkable advancements that aim to improve the precision and efficacy of genetic modifications.

Latest Patents

Nishida's latest patents include a complex for genome editing that boasts stability and minimal side effects. This invention provides a complex containing a nucleic acid sequence-recognizing module linked to a proteolysis tag. The module specifically binds to a target nucleotide sequence in double-stranded DNA, while the tag consists of a peptide containing three hydrophobic amino acid residues at the C-terminal or a peptide with three amino acid residues at the C-terminal, where at least part of the residues is substituted by serine. Another notable patent is a method for converting nucleic acid sequences in cells, which involves stimulating the cell with a factor that induces an endogenous DNA modifying enzyme. This method allows for the alteration of targeted DNA sites by converting, deleting, or inserting nucleotides.

Career Highlights

Throughout his career, Nishida has worked with esteemed institutions such as Kobe University and Nippon Shokubai Co., Ltd. His work has been pivotal in advancing the understanding and application of genome editing technologies.

Collaborations

Nishida has collaborated with notable colleagues, including Akihiko Kondo and Satomi Kojima, contributing to the innovative research in his field.

Conclusion

Keiji Nishida's contributions to genome editing exemplify the potential of innovative technologies in transforming genetic research and applications. His patents reflect a commitment to enhancing the safety and effectiveness of genetic modifications, marking him as a key figure in the scientific community.