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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11845953 B1

PDFFull Text
Date of Patent:
Dec. 19, 2023

Filed:

Mar. 20, 2018

Method for converting nucleic acid sequence of cell specifically converting nucleic acid base of targeted dna using cell endogenous dna modifying enzyme, and molecular complex used therein

Applicant:

National University Corporation Kobe University, Kobe, JP;

Inventors:

Keiji Nishida, Kobe, JP;

Akihiko Kondo, Kobe, JP;

Takayuki Arazoe, Kobe, JP;

Shin Yoshioka, Kobe, JP;

Assignee:

NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, Kobe, JP;

Attorney:

Leydig, Voit & Mayer, Ltd.

Primary Examiner:

David Steadman

Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/01 (2006.01); C12N 9/78 (2006.01); C12N 9/22 (2006.01); C12N 15/90 (2006.01); C12N 15/11 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/85 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Provided is a method for altering a targeted site of a DNA in a cell, including a step of stimulating the cell with a factor inducing a DNA modifying enzyme endogenous to the cell, and bringing a complex of a nucleic acid sequence-recognizing module specifically binding to a target nucleotide sequence in a given DNA and a DNA modifying enzyme-binding module bonded to each other into contact with the DNA to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site.

Find Patent Forward Citations

Nishida, Keiji. (2023). Method for converting nucleic acid sequence of cell specifically converting nucleic acid base of targeted dna using cell endogenous dna modifying enzyme, and molecular complex used therein (U.S. Patent No. 11845953). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11845953

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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