Company Filing History:
Years Active: 2018
Title: **Kathryn M Story: Innovating Insulin Purification and Crystallization**
Introduction
Kathryn M Story, an accomplished inventor based in Harrisonburg, VA, has made significant contributions to the field of biopharmaceuticals with her innovative work on insulin purification and crystallization. With two patents to her name, her research centers on enhancing the processes involved in the production of insulin and its analogs, aiming for better efficiency and quality in diabetes treatment.
Latest Patents
Kathryn's latest inventions include a groundbreaking "Chromatography Process for Purification of Insulin and Insulin Analogs." This process utilizes multiple orthogonal chromatographic purification steps, following enzymatic digestion of the propeptide-insulin precursor. This method successfully removes specific product impurities, improves process consistency, and increases redundancy in insulin purification, particularly for insulin lispro.
Another key patent is the "Method for Preparing Crystalline Insulin or Insulin Analog Compositions." This innovative method outlines the crystallization of insulin or its analogs under alkaline conditions using zinc. The methodology includes filtering to purify the crystals, followed by drying, resulting in high-quality crystalline insulin or insulin analog compositions, with specific examples given for insulin lispro.
Career Highlights
Kathryn is currently associated with Merck Sharp & Dohme Corporation, a leading pharmaceutical company known for its robust research and development in various therapeutic areas. Her focus on insulin-related technologies reflects the company's commitment to advancing diabetes care and treatment options.
Collaborations
Throughout her career, Kathryn has collaborated with other talented professionals including Douglas S Watson and Allison D Ortigosa. These partnerships have facilitated the sharing of knowledge and expertise, further enhancing the quality and impact of their combined research efforts.
Conclusion
Kathryn M Story exemplifies the spirit of innovation in the pharmaceutical industry. Her patents represent not only significant advancements in the purification and formulation of insulin but also highlight the collaborative nature of research and development in healthcare. With her contributions, Kathryn is poised to continue making strides in improving diabetic patient outcomes through her cutting-edge inventions.