The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Aug. 21, 2015
Applicants:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Douglas S. Watson, Elkton, VA (US);
Allison C. Ortigosa, Elkton, VA (US);
Mark C. Sleevi, Longmont, CO (US);
Kathryn M. Story, Elkton, VA (US);
Inventors:
Douglas S. Watson, Harrisonburg, VA (US);
Allison C. Ortigosa, Harrisonburg, VA (US);
Mark C. Sleevi, Longmont, CO (US);
Kathryn M. Story, Harrisonburg, VA (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 9/14 (2006.01); C07K 14/62 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 9/143 (2013.01); A61K 9/145 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); C07K 14/62 (2013.01);
Abstract
A method for crystallizing insulin or insulin analogs under alkaline conditions in the presence of zinc, purifying the crystals by filtering through a filter, and drying the crystals captured on the filter to produce crystalline insulin or insulin analog compositions is described. Method has been exemplified with insulin lispro.