Company Filing History:
4 out of 8,373 
1 out of 207 Years Active: 1994-2007
Title: The Innovations of Katherine M Call: Pioneering Contributions to Genetics
Introduction
Katherine M Call is a notable inventor based in Malden, MA, recognized for her significant contributions to the field of genetics. With a robust portfolio of five patents, she has proven to be a leading innovator in her area of expertise. Her inventions focus on advancements in DNA sequencing and the understanding of genetic markers related to diseases.
Latest Patents
One of Katherine's latest inventions is the "Transposon Mediated Multiplex Sequencing." This automated method enhances the efficiency of transposon-mediated multiplex sequencing of DNA fragments, which are inserted into vectors. The invention focuses on screening out constructs with transposon insertions in vector sequences prior to sequencing. This innovative approach saves valuable time and resources by preventing unnecessary sequencing of vector DNA instead of the fragments of interest.
Another influential patent is related to the "Localization and Characterization of the Wilms' Tumor Gene." This invention delves into the gene associated with the 11p3 locus on the human chromosome, providing methods for analyzing cells for this particular gene. The gene, which primarily expresses in kidney and gonadal tissue, is approximately 50 kb in length and produces four similar mRNA transcripts due to alternative splicing. This research indicates a role in transcription regulation through the polypeptides that include four 'zinc fingers' and a region rich in proline and glutamine.
Career Highlights
Katherine has worked with prestigious institutions such as the Massachusetts Institute of Technology (MIT) and Aventis Pharmaceuticals Inc. Her experiences in these organizations have significantly shaped her innovative approach to genetic research and patent development. The exposure to cutting-edge technology and collaborative environments has undoubtedly contributed to her success.
Collaborations
Throughout her career, Katherine has collaborated with various esteemed professionals, including Thomas M Glaser and Caryn Y Ito. These partnerships reflect her commitment to advancing scientific knowledge and enhancing the understanding of genetic factors concerning human health.
Conclusion
Katherine M Call exemplifies the spirit of innovation in the field of genetics. Her patents demonstrate a remarkable dedication to improving the methods of DNA sequencing and understanding genetic conditions. As she continues her work, Katherine's contributions are sure to leave a lasting impact on both the scientific community and society at large.