The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2001
Filed:
Mar. 09, 1998
Katherine M. Call, Malden, MA (US);
Thomas M. Glaser, Cambridge, MA (US);
Caryn Y. Ito, Chapel Hill, NC (US);
Alan J. Buckler, Brookline, MA (US);
Jerry Pelletier, St. Leonard, CA;
Daniel A. Haber, Cambridge, MA (US);
Elise A. Rose, Oakland, CA (US);
David E. Housman, Newton, MA (US);
Wendy Breuning, Montreal, CA;
Andre Darveau, St. Foy, CA;
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The Wilms' tumor gene associated with 11p3 locus on the human chromosome, as well as a method of analyzing cells for the gene is described and characterized. The gene encodes a transcription unit approximately 50 kb in size and a mRNA of approximately 3 kb, which is expressed in predominantly in kidney and gonadal tissue. The gene is alternative spliced producing four very similar mRNA transcripts. The polypeptides encoded by the Wilms' tumor DNA includes four “zinc fingers” and a region rich in proline and glutamine, suggesting that the polypeptide has a role in transcription regulation.