This inventor holds 4 USPTO granted patents. Top assignee: Massachusetts Institute of Technology. Active years: 1994-2005.
Location History:
- Emeryville, CA (US) (1994)
- Oakland, CA (US) (1998 - 2005)
Company Filing History:
Years Active: 1994-2005
Title: The Innovative Contributions of Elise A. Rose
Introduction
Elise A. Rose is a prominent inventor based in Oakland, CA. She has made significant contributions to the field of genetics, particularly in the study of the Wilms' tumor gene. With a total of 4 patents to her name, her work has had a profound impact on medical research and understanding of genetic disorders.
Latest Patents
One of her latest patents focuses on the localization and characterization of the Wilms' tumor gene associated with the 11p3 locus on the human chromosome. This patent describes a method of analyzing cells for the gene, which encodes a transcription unit approximately 50 kb in size and an mRNA of approximately 3 kb. The gene is predominantly expressed in kidney and gonadal tissue. Notably, it undergoes alternative splicing, producing four very similar mRNA transcripts. The polypeptides encoded by the Wilms' tumor DNA include four "zinc fingers" and a region rich in proline and glutamine, suggesting a role in transcription regulation.
Career Highlights
Elise A. Rose is affiliated with the Massachusetts Institute of Technology, where she continues her research and innovation in genetics. Her work has been instrumental in advancing the understanding of genetic factors in cancer, particularly in pediatric oncology.
Collaborations
Throughout her career, Elise has collaborated with notable colleagues, including Thomas M. Glaser and Alan J. Buckler. These collaborations have further enriched her research and contributed to the advancement of knowledge in her field.
Conclusion
Elise A. Rose's innovative work in the field of genetics, particularly regarding the Wilms' tumor gene, showcases her dedication to advancing medical research. Her contributions continue to influence the understanding of genetic disorders and their implications for treatment.