This inventor holds 4 USPTO granted patents. Top assignee: Massachusetts Institute of Technology. Active years: 1994-2005.
Location History:
- Belmont, MA (US) (1998)
- Cambridge, MA (US) (1994 - 2001)
- Ann Arbor, MI (US) (2005)
Company Filing History:
Years Active: 1994-2005
Title: The Innovations of Thomas M. Glaser
Introduction
Thomas M. Glaser is a notable inventor based in Ann Arbor, MI (US). He has made significant contributions to the field of genetics, particularly in the study of the Wilms' tumor gene. With a total of 4 patents to his name, Glaser's work has had a profound impact on understanding genetic disorders.
Latest Patents
One of Glaser's latest patents focuses on the localization and characterization of the Wilms' tumor gene associated with the 11p3 locus on the human chromosome. This patent describes a method of analyzing cells for the gene, which encodes a transcription unit approximately 50 kb in size and an mRNA of approximately 3 kb. The gene is predominantly expressed in kidney and gonadal tissue. It is alternatively spliced, producing four very similar mRNA transcripts. The polypeptides encoded by the Wilms' tumor DNA include four "zinc fingers" and a region rich in proline and glutamine, suggesting a role in transcription regulation.
Career Highlights
Glaser is affiliated with the Massachusetts Institute of Technology, where he continues to advance research in genetics. His work has been instrumental in shedding light on the complexities of genetic expression and regulation.
Collaborations
Some of his notable coworkers include Katherine M. Call and Jerry M. Pelletier. Their collaborative efforts have further enriched the research landscape in which Glaser operates.
Conclusion
Thomas M. Glaser's contributions to the field of genetics, particularly through his patents related to the Wilms' tumor gene, highlight his innovative spirit and dedication to scientific advancement. His work continues to influence the understanding of genetic disorders and their implications.