Company Filing History:
Years Active: 2007-2011
Title: The Innovations of Karen S De Jongh
Introduction
Karen S De Jongh is a prominent inventor based in Seattle, WA, known for her significant contributions to the field of biotechnology. With a total of three patents to her name, she has made remarkable advancements in medical research and applications.
Latest Patents
One of her latest patents is titled "Method for activating prethrombin-1." This invention discloses methods for converting prethrombin-1 to thrombin. An aqueous solution of prethrombin-1 is applied to oscutarin-C immobilized on a solid support, providing from 500 mg to 4000 mg of prethrombin-1 per mL of the solid support. The contact time between the prethrombin-1 and the oscutarin-C ranges from 1.8 to 3.5 minutes. The resulting active thrombin can be captured on an ion exchange chromatography medium or an affinity chromatography medium. Another significant patent is focused on "IL-21 production in prokaryotic hosts." This patent describes expression vectors and methods for large-scale production of IL-21. The vectors utilize the IL-21 coding sequence with specific nucleotide changes to optimize codons and mRNA secondary structure for translation. Using these expression vectors, the IL-21 gene was produced at levels greater than 1 g/L in fed batch fermentation.
Career Highlights
Karen S De Jongh is currently employed at Zymogenetics, Inc., where she continues to innovate and contribute to the field of biotechnology. Her work has been instrumental in advancing therapeutic methods and improving production processes in the industry.
Collaborations
Throughout her career, Karen has collaborated with notable colleagues, including Bruce L Zamost and Hong Yan Liu. These partnerships have fostered a collaborative environment that enhances research and development efforts.
Conclusion
Karen S De Jongh's contributions to biotechnology through her patents and work at Zymogenetics, Inc. highlight her role as a leading inventor in her field. Her innovative methods and collaborative spirit continue to drive advancements in medical research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.