Karen Nazaretian Allen

Title: Karen Nazaretian Allen: Innovator in Biosensor Technology

Introduction

Karen Nazaretian Allen is a prominent inventor based in Weston, MA (US). She has made significant contributions to the field of biosensor technology, holding a total of three patents. Her work focuses on innovative solutions for detecting nicotine and understanding the mechanisms of specific biological processes.

Latest Patents

One of her latest patents is an enzyme-based electrochemical nicotine biosensor. This invention describes an amperometric biosensor designed for measuring nicotine concentration. It includes a wearable nicotine biosensor device and a biosensor capable of detecting nicotine in smoke. The biosensor utilizes nicotine-catalyzing enzymes, such as NicA2 or its mutant forms, to achieve its functionality. Another notable patent is related to the method of identifying inhibitors of Tie-2. This invention involves polypeptides that comprise the ligand binding domain of Tie-2 and crystalline forms of these polypeptides. The invention aims to determine the three-dimensional structure of the catalytic domain of Tie-2, which can be used to design and identify potential inhibitors of Tie-2 activity.

Career Highlights

Throughout her career, Karen has worked with prestigious institutions, including Boston University and the Massachusetts Institute of Technology. Her research has significantly advanced the understanding of biosensors and their applications in health monitoring.

Collaborations

Karen has collaborated with notable colleagues, including Barbara Imperiali and Katherine J. Franz. These partnerships have contributed to her innovative research and development in the field.

Conclusion

Karen Nazaretian Allen is a trailblazer in biosensor technology, with her inventions paving the way for advancements in nicotine detection and biological research. Her contributions continue to impact the scientific community and enhance our understanding of critical health-related issues.