The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2022

Filed:

Feb. 05, 2021
Applicant:

Trustees of Boston University, Boston, MA (US);

Inventors:

James Galagan, Needham, MA (US);

Mark W. Grinstaff, Brookline, MA (US);

Uros Kuzmanovic, Brookline, MA (US);

Mingfu Chen, Boston, MA (US);

Margarita Alexandrovna Tararina, Bryn Mawr, PA (US);

Karen Nazaretian Allen, Weston, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/1486 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); G01N 33/487 (2006.01); C12Q 1/26 (2006.01); C12Q 1/00 (2006.01); G01N 27/327 (2006.01); A61B 10/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1486 (2013.01); A61B 5/14517 (2013.01); A61B 5/4845 (2013.01); C12Q 1/004 (2013.01); C12Q 1/005 (2013.01); C12Q 1/26 (2013.01); G01N 27/3272 (2013.01); G01N 33/48714 (2013.01); A61B 10/0064 (2013.01);
Abstract

Described herein is an amperometric biosensor, e.g., chronoamperometric biosensor for the measurement of the concentration of nicotine. Also disclosed herein is a wearable nicotine biosensor device and a biosensor that detects nicotine in smoke. The biosensor disclosed herein comprises a nicotine-catalyzing enzyme, such as NicA2 or mutant NicA2 enzymes. Also described herein are systems comprising said amperometric biosensor, e.g., chronoamperometric biosensor and methods of using said chronoamperometric biosensor.


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