Location History:
- Köln, DE (2008)
- Glauchau, DE (2011 - 2012)
Company Filing History:
Years Active: 2008-2012
Title: Juliana Helfrich: Innovator in Electroporation Technology
Introduction
Juliana Helfrich is a prominent inventor based in Glauchau, Germany. She has made significant contributions to the field of biotechnology, particularly in the area of electroporation technology. With a total of seven patents to her name, her work focuses on methods for introducing biologically active molecules into cells.
Latest Patents
One of her latest patents is a buffer solution for electroporation and a method comprising the use of the same. This invention involves a method for introducing biologically active molecules into animal or human cells using an electric current. The process includes suspending the cells and dissolving the biologically active molecules in a buffer solution that contains HEPES and at least 10 mmol·1 magnesium ions (Mg). The buffer solution has a buffer capacity of at least 20 mmol·1·pH at a change in the pH from 7 to 8 and at a temperature of 25°C, with an ionic strength of at least 200 mmol·1. An electric voltage is then applied to the suspension.
Another notable patent is a circuit arrangement for injecting nucleic acids and other biologically active molecules into the nucleus of higher eukaryotic cells using electrical current. This invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eukaryotic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
Career Highlights
Juliana has worked with several reputable companies throughout her career, including Lonza Cologne GmbH and Amaxa AG. Her experience in these organizations has contributed to her expertise in the field of biotechnology and patent development.
Collaborations
Throughout her career, Juliana has collaborated with notable colleagues such as Gudula Riemen and Elke Lorbach. These partnerships have further enhanced her innovative work and contributions to the field.
Conclusion
Juliana Helfrich is a distinguished inventor whose work in electroporation technology has paved the way for advancements in biotechnology. Her patents reflect her commitment to innovation and her impact on the scientific community.