Company Filing History:
7 out of 3,439 
1 out of 1,215 
Years Active: 1994-2013
Title: Joseph Shiloach: Innovator in Immunogenic Conjugates
Introduction
Joseph Shiloach is a prominent inventor based in Rockville, MD (US). He has made significant contributions to the field of immunology, holding a total of 8 patents. His work focuses on developing methods for preparing immunogenic conjugates, which are crucial for advancing vaccine technology.
Latest Patents
Among his latest patents, Joseph Shiloach has developed methods for making an immunogenic conjugate that includes a hapten or an antigen covalently linked to a carrier. These methods involve reacting a first agent with a dihydrazide to create a hydrazine-modified first agent, which can be a hapten, an antigen, or a carrier. Additionally, a second agent is reacted with a benzaldehyde compound to produce a benzaldehyde-modified second agent. The final step involves combining the hydrazine-modified first agent with the benzaldehyde-modified second agent to yield an immunogenic conjugate linked via a hydrazone linkage. Another notable invention relates to improved methods of producing and recovering sporulation-deficient mutant strains, particularly for generating recombinant protective antigens that are protease resistant. These advancements are essential for eliciting immunogenic responses in humans, providing protection against bacterial infections such as inhalation anthrax, cutaneous anthrax, and gastrointestinal anthrax.
Career Highlights
Joseph Shiloach has had a distinguished career, working with esteemed organizations such as the National Institutes of Health, a component of the US Department of Health & Human Services. His contributions to the field have been recognized and have had a lasting impact on immunological research.
Collaborations
Throughout his career, Joseph has collaborated with notable colleagues, including Rachel Schneerson and John B. Robbins. These partnerships have furthered his research and innovation in the field of immunology.
Conclusion
Joseph Shiloach's work in developing immunogenic conjugates and protective antigens showcases his dedication to advancing medical science. His patents and collaborations reflect his significant contributions to immunology and public health.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.