Inventors with similar research interests:
Location History:
- Menlo Park, CA (US) (1998)
- Waban, MA (US) (2000)
- Cambridge, MA (US) (1993 - 2005)
- Somerville, MA (US) (2007)
- Newton Centre, MA (US) (2000 - 2016)
- Newton Center, MA (US) (2009 - 2017)
- Newton, MA (US) (2000 - 2024)
Company Filing History:
55 out of 700 
48 out of 8,369 
27 out of 43 
Years Active: 1993-2025
Title: Joseph M Jacobson: Pioneering Innovator in Gene Editing Technologies
Introduction:
Joseph M Jacobson, hailing from Newton, MA, is a renowned inventor and scientist whose groundbreaking work in gene editing technologies has earned him widespread recognition. With an impressive portfolio of 133 patents, Jacobson has made significant contributions to the field of molecular biology and has helped shape the future of genetic research.
Latest Patents:
One of Jacobson's recent focuses has been on the applications of engineered Cas9 variants on single-base PAM targets. These variants include an ScCas9 protein called Sc+, which features a threonine-to-lysine substitution mutation at position 1227 in its amino acid sequence. Another variant, Sc++ incorporates both the threonine-to-lysine substitution mutation and a substitution of residues ADKKLRKRSGKLATE [SEQ ID No. 4] in position 365-379 in the ScCas9 open reading frame. Jacobson's latest patents showcase his commitment to advancing the potential of CRISPR-associated DNA endonucleases and altering the expression of gene products.
Career Highlights:
Joseph M Jacobson's career spans across significant institutions and companies. He has been associated with E Ink Corporation, a pioneering company known for its electronic ink technology used in e-readers and displays. His contributions to E Ink Corporation have propelled advancements in electronic paper displays, transforming the way we interact with digital information.
Jacobson's collaboration with the Massachusetts Institute of Technology (MIT) has been instrumental in driving cutting-edge research in various emerging fields. His multidisciplinary approach, combining engineering, molecular biology, and nanotechnology, has led to groundbreaking breakthroughs in medical and biological sciences.
Collaborations:
Throughout his career, Joseph M Jacobson has collaborated with esteemed colleagues, further reinforcing his innovative prowess. Notably, he has worked closely with Jonathan D Albert, a brilliant scientist and researcher known for his contributions to biotechnology. Their partnership has undoubtedly sparked new insights and led to remarkable advancements in the field.
Another significant collaborator of Jacobson is Barrett Comiskey, an entrepreneur and inventor. Comiskey co-founded E Ink Corporation and was instrumental in the commercialization of electronic ink technology. Together, Comiskey and Jacobson have harnessed their expertise to revolutionize electronic displays and bring innovative products to market.
Conclusion:
Joseph M Jacobson's remarkable journey as an inventor and scientist has left an indelible mark on the field of molecular biology, specifically in the area of gene editing technologies. With 133 patents, which include advancements in CRISPR-associated DNA endonucleases and the alteration of gene product expression, Jacobson's contributions continue to shape the landscape of genetic research. His collaborations with esteemed colleagues, such as Jonathan D Albert and Barrett Comiskey, highlight his commitment to fostering innovation through interdisciplinary collaboration. As we move forward into a future of advanced genetic technologies, Joseph M Jacobson's work will undoubtedly leave a lasting legacy.
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