The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Mar. 21, 2018
Applicant:

Gen9, Inc., Boston, MA (US);

Inventors:

Joseph Jacobson, Newton, MA (US);

Larry Li-Yang Chu, Cambridge, MA (US);

Assignee:

Gen9, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6811 (2018.01); C12Q 1/6837 (2018.01); C12N 15/10 (2006.01); B01J 19/00 (2006.01);
U.S. Cl.
CPC ...
B01J 19/0046 (2013.01); C12N 15/1031 (2013.01); C12Q 1/6811 (2013.01); C12Q 1/6837 (2013.01); B01J 2219/00608 (2013.01); B01J 2219/00722 (2013.01);
Abstract

Methods and apparatus relate to the synthesis of high fidelity polynucleotides and to the reduction of sequence errors generated during synthesis of nucleic acids on a solid support. Specifically, design of support-bound template oligonucleotides is disclosed. Assembly methods include cycles of annealing, stringent wash and extension of polynucleotides comprising a sequence region complementary to immobilized template oligonucleotides. The error free synthetic nucleic acids generated therefrom can be used for a variety of applications, including synthesis of biofuels and value-added pharmaceutical products.


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