Company Filing History:
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1 out of 832,843 Years Active: 2012-2018
Title: Joseph G Matuck: Innovator in Cell Culture Technology
Introduction
Joseph G Matuck is a notable inventor based in Worcester, MA (US), recognized for his contributions to the field of cell culture technology. He holds a total of 9 patents, showcasing his innovative approach to enhancing protein production in mammalian cell cultures.
Latest Patents
Among his latest patents, Matuck has developed a modified serum-free cell culture medium. This invention describes improved methods and compositions for producing recombinant proteins, such as antibodies, in mammalian cell culture. The invention also provides enhanced cell culture media, including production media, feed solutions, and combination feeds, aimed at improving protein productivity. Another significant patent involves the use of metal ions for modulating protein glycosylation profiles of recombinant proteins. This research demonstrates that growth media supplemented with metal ions can influence the glycosylation profile of recombinant proteins expressed in various eukaryotic cell lines. Notably, the addition of ferric salts significantly increased the percentage of galactosylated N-glycan species, showcasing a concentration-dependent effect without adversely affecting cell viability.
Career Highlights
Throughout his career, Joseph G Matuck has worked with prominent companies such as AbbVie Inc. and Abbott Laboratories Corporation. His work in these organizations has contributed to advancements in biopharmaceutical development and cell culture methodologies.
Collaborations
Matuck has collaborated with several professionals in his field, including Itzcoatl A Pla and John C Fann. These collaborations have further enriched his research and innovations in cell culture technology.
Conclusion
Joseph G Matuck's innovative work in cell culture technology and his numerous patents highlight his significant contributions to the field. His research continues to influence the production of recombinant proteins, paving the way for advancements in biopharmaceuticals.