This inventor holds 8 USPTO granted patents and 15 published patent applications. Top assignees: Decibel Therapeutics, Inc., Regeneron Pharmaceuticals, Inc.. Active years: 2023-2026.
Company Filing History:
7 out of 14 
3 out of 1,473 
Years Active: 2023-2026
Title: Joseph Burns: Innovator in Hearing Loss Treatment
Introduction
Joseph Burns is a notable inventor based in Newton, MA (US), recognized for his contributions to the field of auditory health. He holds a total of 8 patents, focusing on innovative methods for treating sensorineural hearing loss. His work has the potential to significantly impact the lives of individuals suffering from hearing impairments.
Latest Patents
One of his latest patents is titled "Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems." This patent features compositions and methods aimed at treating sensorineural hearing loss and auditory neuropathy, particularly those associated with mutations in the otoferlin (OTOF) gene. The invention includes a first nucleic acid vector that encodes an N-terminal portion of the OTOF protein and a second nucleic acid vector that encodes a C-terminal portion of the OTOF protein. These vectors are designed to enhance the expression of OTOF in subjects, such as humans suffering from sensorineural hearing loss.
Another significant patent by Joseph Burns is "Myosin 15 promoters and uses thereof." This patent provides polynucleotides containing regions of the Myosin 15 (Myo15) promoter, along with vectors that can promote the expression of a transgene specifically in hair cells. The described polynucleotides may be operably linked to a therapeutic transgene, facilitating hair cell-specific expression and offering potential treatments for individuals at risk of hearing loss or vestibular dysfunction.
Career Highlights
Throughout his career, Joseph Burns has worked with prominent companies in the biotechnology sector, including Decibel Therapeutics, Inc. and Regeneron Pharmaceuticals, Inc. His experience in these organizations has contributed to his expertise in developing innovative solutions for hearing loss.
Collaborations
Joseph has collaborated with notable professionals in his field, including Kathryn Ellis and Adam Palermo. These partnerships have likely enhanced his research and development efforts, leading to significant advancements in auditory health.
Conclusion
Joseph Burns is a pioneering inventor whose work in the treatment of hearing loss showcases his commitment to improving auditory health. His innovative patents and collaborations reflect his dedication to advancing medical science and providing solutions for those affected by hearing impairments.