Seattle, WA, United States of America

Joseph A Beavo


 


Average Co-Inventor Count = 4.4

ph-index = 6

Forward Citations = 91(Granted Patents)


Company Filing History:


Years Active: 1995-2010

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17 patents (USPTO):Explore Patents

Title: Joseph A Beavo: Innovator in Phosphodiesterase Research

Introduction

Joseph A Beavo is a prominent inventor based in Seattle, WA (US). He has made significant contributions to the field of biochemistry, particularly in the study of phosphodiesterases. With a total of 17 patents, his work has advanced our understanding of these important enzymes.

Latest Patents

Among his latest patents, Beavo has developed novel purified and isolated nucleotide sequences encoding mammalian Ca/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). This invention includes the corresponding recombinant expression products, immunological reagents, and methods for identifying compounds that modulate the enzymatic activity of these expression products. Another significant patent provides isolated full-length nucleic acid molecules encoding a novel PDE protein, along with methods for their use. This includes peptide nucleic acids (PNA) and antisense molecules that interact with the nucleic acid molecules, as well as agonists, antibodies, antagonists, or inhibitors of the activity of these novel PDE proteins. These compositions are valuable for diagnosing, preventing, or treating conditions related to the presence or deficiency of these proteins.

Career Highlights

Joseph A Beavo has had a distinguished career, working with notable institutions such as the University of Washington and Icos Corporation. His research has been pivotal in the development of therapeutic strategies targeting phosphodiesterases.

Collaborations

Throughout his career, Beavo has collaborated with esteemed colleagues, including William K Sonnenburg and Harry Charbonneau. Their combined expertise has contributed to the advancement of research in this field.

Conclusion

Joseph A Beavo's innovative work in phosphodiesterase research has led to numerous patents and significant advancements in biochemistry. His contributions continue to impact the scientific community and pave the way for future discoveries.

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