The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Oct. 30, 2003
Applicants:

Joseph A. Beavo, Seattle, WA (US);

Kelley J. Bentley, Seattle, WA (US);

Harry Charbonneau, W. Lafayette, IN (US);

William K. Sonnenburg, Seattle, WA (US);

Inventors:

Joseph A. Beavo, Seattle, WA (US);

Kelley J. Bentley, Seattle, WA (US);

Harry Charbonneau, W. Lafayette, IN (US);

William K. Sonnenburg, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C12N 1/21 (2006.01); C12N 5/22 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.


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