The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 1997
Filed:
Jun. 07, 1995
Joseph A Beavo, Seattle, WA (US);
Jackie D Corbin, Nashville, TN (US);
Kenneth M Ferguson, Bothell, WA (US);
Sharron H Francis, Nashville, TN (US);
Ann Kadlecek, Seattle, WA (US);
Kate Loughney, Seattle, WA (US);
Linda M McAllister-Lucas, Nashville, TN (US);
William K Sonnenburg, Mountlake Terrace, WA (US);
Melissa K Thomas, Boston, MA (US);
ICOS Corporation, Bothell, WA (US);
Vanderbilt University, Nashville, TN (US);
Board of Regents of the University of Washington, Seattle, WA (US);
Abstract
The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.