Location History:
- Berkshire, GB (2001)
- San Diego, CA (US) (2005)
- The Oxford Science Park, GB (2007)
- Oxford, GB (2008)
Company Filing History:
Years Active: 2001-2008
Title: Innovations by Inventor Jonathan Rohll
Introduction
Jonathan Rohll, an accomplished inventor based at The Oxford Science Park in Great Britain, has made significant contributions to the field of vector systems. With a portfolio of four patents, his innovative work primarily focuses on advancing retroviral vector technologies.
Latest Patents
Among his latest patents, one notable invention is a vector system that incorporates a mutated post-transcriptional regulatory element. This invention specifically pertains to a mutated WPRE sequence capable of efficiently expressing nucleotides of interest within a retroviral vector system. Additionally, the patent addresses methods for delivering and expressing these nucleotides in target cells. Another key patent involves retroviral vector genomes and systems, including a genome with two or more Nucleotides of Interest (NOIs) linked by one or more Internal Ribosome Entry Sites. Furthermore, it features a lentiviral vector genome devised for treating neurodegenerative disorders, which encodes essential enzymes like tyrosine hydroxylase and GTP-cyclohydrolase I, along with the option for Aromatic Amino Acid Dopa Decarboxylase.
Career Highlights
Jonathan has been associated with reputable companies in the biotechnology field, notably Oxford Biomedica Limited and Oxford Biomedia Limited. His tenure in these organizations has allowed him to enhance his research and innovate in the area of gene delivery systems.
Collaborations
Throughout his career, Jonathan Rohll has collaborated with esteemed colleagues such as Alan John Kingsman and Kyriacos Andreou Mitrophanous. These partnerships have contributed to his advancements in vector technology and have fostered a collaborative environment for innovation.
Conclusion
With a focus on cutting-edge technologies in retroviral vectors, Jonathan Rohll's work exemplifies the pivotal role inventors play in biotech advancements. His patents not only hold promise for therapeutic applications but also represent significant milestones in scientific research, further underscoring the importance of innovation in the field.