The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2007

Filed:

Apr. 07, 2003
Applicants:

Alan John Kingsman, The Oxford Science Park, GB;

Nicholas D. Mazarakis, The Oxford Science Park, GB;

Enca Martin-rendon, Sanford-on-Thames, GB;

Mimoun Azzouz, The Oxford Science Park, GB;

Jonathan Rohll, The Oxford Science Park, GB;

Inventors:

Alan John Kingsman, The Oxford Science Park, GB;

Nicholas D. Mazarakis, The Oxford Science Park, GB;

Enca Martin-Rendon, Sanford-on-Thames, GB;

Mimoun Azzouz, The Oxford Science Park, GB;

Jonathan Rohll, The Oxford Science Park, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/867 (2006.01); C12N 15/63 (2006.01); C12N 15/64 (2006.01); C12N 5/10 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.


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