Company Filing History:
6 out of 2,620 
1 out of 282 
Years Active: 2011-2023
Title: Innovations and Contributions of Jonathan A Epstein
Introduction
Jonathan A Epstein is a prominent inventor based in Radnor, PA (US). He has made significant contributions to the field of medical science, particularly in the treatment of heart disease. With a total of 6 patents to his name, Epstein's work has the potential to impact countless lives.
Latest Patents
Epstein's latest patents include groundbreaking methods for treating heart disease via redirected T cell immunotherapies. This invention encompasses compositions and methods aimed at treating heart disease and/or heart failure. One embodiment of the treatment involves administering a cell that has been genetically modified to express a chimeric antigen receptor (CAR), which includes an antigen binding domain specific for fibroblast activation protein (FAP). Another embodiment focuses on administering a cell genetically modified to express a T cell receptor (TCR) that is specific for an activated fibroblast. Additionally, he has developed methods utilizing HDAC inhibitors for the treatment of cardiac rhythm disorders. This invention provides methods to ameliorate or reduce the extent of cardiac arrhythmia disorders by administering an inhibitor of histone deacetylase enzyme (HDAC).
Career Highlights
Throughout his career, Jonathan A Epstein has worked with esteemed institutions such as the University of Pennsylvania and The Children's Hospital of Philadelphia. His work in these organizations has allowed him to collaborate with leading experts in the field and contribute to innovative research.
Collaborations
Epstein has collaborated with notable colleagues, including Peter J Gruber and Ibrahim Abdullah. These partnerships have further enhanced his research and development efforts in the medical field.
Conclusion
Jonathan A Epstein's contributions to medical science through his patents and collaborations highlight his dedication to advancing treatments for heart disease. His innovative approaches have the potential to transform patient care and improve health outcomes.