The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Dec. 16, 2013
Applicants:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
Peter J. Gruber, Swarthmore, PA (US);
Jonathan A. Epstein, Radnor, PA (US);
Ibrahim Abdullah, Rigley Pk, PA (US);
Assignees:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
CHILDREN'S HOSPITAL OF PHILADELPHIA, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); A61K 31/16 (2006.01); A61K 31/185 (2006.01); A61K 31/00 (2006.01); A61K 31/19 (2006.01);
U.S. Cl.
CPC ...
A61K 31/185 (2013.01); A61K 31/00 (2013.01); A61K 31/165 (2013.01); A61K 31/19 (2013.01);
Abstract
The present invention provides methods of ameliorating or reducing the extent of ischemic injury, reperfusion injury, and myocardial infarction, by administering an inhibitor of histone deacetylase enzyme (HDAC) or an inhibitor of DNA methyltransferase enzyme (DNMT).