The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Mar. 18, 2010
Applicants:

Jonathan A. Epstein, Radnor, PA (US);

Reynold Panettieri, Bensalem, PA (US);

Inventors:

Jonathan A. Epstein, Radnor, PA (US);

Reynold Panettieri, Bensalem, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/573 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 31/46 (2006.01); A61K 31/522 (2006.01); A61P 11/08 (2006.01); A61P 11/00 (2006.01); A61P 11/14 (2006.01); A61P 11/06 (2006.01); A61K 31/16 (2006.01); A61K 31/439 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/16 (2013.01); A61K 31/165 (2013.01); A61K 31/167 (2013.01); A61K 31/439 (2013.01); A61K 31/522 (2013.01); A61K 31/573 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides methods for dilating the bronchi or bronchioles and relaxing a pulmonary smooth muscle in a subject by treating the subject with a pharmaceutical composition, which includes a Histone deacetylase (HDAC) inhibitor. The ability to dilate the bronchi or bronchioles and relax a pulmonary smooth muscle according to the methods of the invention allows treating, alleviating, or inhibiting bronchoconstrictive diseases or disorders and symptoms associated or derived from bronchoconstrictive diseases.


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