Company Filing History:
5 out of 1,373 
4 out of 1,209 
1 out of 443 
Years Active: 2014-2023
Title: Jon C Aster: Innovator in Cancer Research
Introduction
Jon C Aster is a prominent inventor based in Lexington, MA (US), known for his significant contributions to cancer research. He holds 5 patents that focus on innovative methods for diagnosing and treating conditions related to cancer and cellular resistance.
Latest Patents
Aster's latest patents include groundbreaking work on methods for determining and treating cellular resistance to ADP-ribosylating toxins. This invention identifies DPH1 and other members of the diphthamide synthesis pathway as biomarkers of resistance, providing new avenues for treatment. Another notable patent involves diagnostic and treatment methods for subjects with cancer, particularly those characterized by Notch pathway activation mutations or resistance to Notch pathway inhibitors. These inventions represent significant advancements in the field of oncology.
Career Highlights
Throughout his career, Jon C Aster has worked with esteemed institutions such as Brigham and Women's Hospital and Dana-Farber Cancer Institute. His work has been instrumental in advancing cancer treatment methodologies and improving patient outcomes.
Collaborations
Aster has collaborated with notable colleagues, including Bradley Bernstein and James Elliott Bradner, further enhancing the impact of his research in the medical community.
Conclusion
Jon C Aster's innovative work in cancer research and his numerous patents highlight his dedication to improving treatment options for patients. His contributions continue to shape the future of oncology and provide hope for those affected by cancer.