The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Jul. 21, 2009
Applicants:
Christopher French, Boston, MA (US);
Jon Aster, Lexington, MA (US);
Matthias Hofer, Chicago, IL (US);
James Bradner, Cambridge, MA (US);
Inventors:
Christopher French, Boston, MA (US);
Jon Aster, Lexington, MA (US);
Matthias Hofer, Chicago, IL (US);
James Bradner, Cambridge, MA (US);
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/40 (2006.01); A01N 43/38 (2006.01); A01N 43/08 (2006.01); A01N 37/28 (2006.01); A61K 31/33 (2006.01); A61K 38/00 (2006.01); A61K 38/12 (2006.01); A61K 31/44 (2006.01); A61K 31/405 (2006.01); A61K 31/34 (2006.01); A61K 31/205 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is directed, inter alia, to methods of treating NUT midline carcinoma (NMC) by administering compounds that promote increased histone acetylation. The invention also includes assay methods for determining the responsiveness of NMC to specific histone deacetylases and other compounds.