Company Filing History:
Years Active: 2019-2024
Title: John Tabone: Innovator in Nucleic Acid Polymerization
Introduction
John Tabone is a notable inventor based in Kirkland, WA (US), recognized for his contributions to the field of nucleic acid polymerization. With a total of three patents to his name, he has made significant advancements that enhance the efficiency of DNA replication and sequencing techniques.
Latest Patents
One of his latest patents is titled "Enhancement of nucleic acid polymerization by aromatic compounds." This invention relates to compounds, methods, and compositions that improve nucleic acid polymerization, including DNA replication through in vitro primer extension. The technology aims to generate polymers suitable for nanopore-based single molecule sequencing of DNA templates. The patent provides a nucleic acid polymerase reaction composition that includes polymerization enhancement moieties, which significantly boost DNA polymerase activity with nucleotide analogs. This results in improved lengths of primer extension products, making them more effective for sequencing applications.
Another significant patent by John Tabone is "Phosphoroamidate esters, and use and synthesis thereof." This patent discloses phosphoramidate esters and related nucleotide analogs that are useful in polynucleotide sequencing techniques. It also outlines synthetic methods for preparing these compounds, which include nucleotide phosphoramidate analogs modified on the alpha-phosphate. This modification enables the attachment of various application-specific substituents, such as tether molecules.
Career Highlights
Throughout his career, John Tabone has worked with prominent companies in the biotechnology sector, including Stratos Genomics, Inc. and Roche Sequencing Solutions, Inc. His work in these organizations has contributed to the advancement of sequencing technologies and methodologies.
Collaborations
John has collaborated with notable professionals in his field, including Mark Stamatios Kokoris and Melud Nabavi. These collaborations have further enriched his research and development efforts.
Conclusion
John Tabone's innovative work in nucleic acid polymerization has led to significant advancements in DNA sequencing technologies. His patents reflect a commitment to enhancing scientific methodologies, making him a valuable contributor to the field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.