The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Dec. 27, 2018
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Mark Stamatios Kokoris, Bothell, WA (US);
John Tabone, Kirkland, WA (US);
Melud Nabavi, Seattle, WA (US);
Aaron Jacobs, Seattle, WA (US);
Dylan O'Connell, Seattle, WA (US);
Drew Goodman, Seattle, WA (US);
Lacey Merrill, Seattle, WA (US);
Jagadeeswaran Chandrasekar, Seattle, WA (US);
Kendall Berg, Seattle, WA (US);
Samantha Vellucci, Seattle, WA (US);
Jessica Vellucci, Bremerton, WA (US);
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Abstract
The invention relates to compounds, methods and compositions for improving on nucleic acid polymerization, including DNA replication by in vitro primer extension to generate, for example, polymers for nanopore-based single molecule sequencing of a DNA template. A nucleic acid polymerase reaction composition is provided with polymerization enhancement moieties, which allows enhanced DNA polymerase activity with nucleotide analogs, resulting in improved length of primer extension products for sequencing applications.