Company Filing History:
Years Active: 2022-2024
Title: Drew Goodman: Innovator in Nucleic Acid Polymerization
Introduction
Drew Goodman is a prominent inventor based in Seattle, WA (US), known for his significant contributions to the field of nucleic acid polymerization. With a total of 2 patents, he has made strides in enhancing DNA replication and sequencing technologies.
Latest Patents
Goodman's latest patents include innovations that focus on improving nucleic acid polymerization. One of his notable inventions is the enhancement of nucleic acid polymerization by aromatic compounds. This invention relates to compounds, methods, and compositions that improve nucleic acid polymerization, including DNA replication through in vitro primer extension. This technology is particularly useful for generating polymers for nanopore-based single molecule sequencing of DNA templates. The nucleic acid polymerase reaction composition provided allows for enhanced DNA polymerase activity with nucleotide analogs, resulting in improved lengths of primer extension products for sequencing applications.
Another significant patent is for DPO4 polymerase variants with improved accuracy. This patent presents recombinant DPO4-type DNA polymerase variants that have amino acid substitutions, which confer modified properties for enhanced single molecule sequencing applications. These properties include improved binding and accurate incorporation of bulky nucleotide analog substrates into daughter strands. The patent also includes compositions comprising such DPO4 variants and nucleotide analogs, as well as nucleic acids encoding the polymerases with the desired phenotypes.
Career Highlights
Throughout his career, Drew Goodman has worked with notable companies such as Roche Sequencing Solutions, Inc. and Stratos Genomics, Inc. His work in these organizations has contributed to advancements in sequencing technologies and nucleic acid research.
Collaborations
Goodman has collaborated with several professionals in his field, including Mark Stamatios Kokoris and Aaron Jacobs. These collaborations have further enriched his research and innovations in nucleic acid polymerization.
Conclusion
Drew Goodman is a key figure in the field of nucleic acid polymerization, with a focus on enhancing DNA replication and sequencing technologies. His patents and career achievements reflect his dedication to advancing scientific research and innovation.