Location History:
- Overland Park, KS (US) (1987)
- Concord, CA (US) (1995)
- Occidental, CA (US) (1995)
- Palo Alto, CA (US) (2007 - 2010)
- Dallas, TX (US) (2001 - 2013)
- New York, NY (US) (2018 - 2024)
Company Filing History:
5 out of 2,488 
1 out of 1 
1 out of 1 Years Active: 1987-2025
Title: Innovations of John O'Neill
Introduction
John O'Neill is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of medical technology, particularly in the area of organ support and recovery. With a total of 13 patents, O'Neill's work has the potential to revolutionize organ transplantation and recovery processes.
Latest Patents
One of O'Neill's latest patents is a cross-circulation platform for the recovery, regeneration, and maintenance of extracorporeal organs. This invention describes systems, methods, and devices related to normothermic extracorporeal support of an organ, tissue, or bioengineered graft. The cross-circulation (XC) perfusion allows for prolonged support via an XC perfusion circuit connected to an extracorporeal host, such as an animal or organ transplant recipient. The XC perfusion circuit features auto-regulation of blood flow based on the trans-organ blood pressure difference between arterial and venous pressure. This innovative approach enabled 36 hours of normothermic perfusion, maintaining healthy lungs without significant changes in physiological parameters and facilitating the recovery of injured lungs. The extended support also allowed for multiscale therapeutic interventions in all extracorporeal lungs, with the lungs exceeding transplantation criteria.
Career Highlights
Throughout his career, John O'Neill has worked with notable institutions, including Columbia University. His research and inventions have garnered attention for their potential impact on medical practices and patient outcomes.
Collaborations
O'Neill has collaborated with esteemed colleagues such as Gordana Vunjak-Novakovic and Matthew D Bacchetta. Their combined expertise has contributed to the advancement of innovative solutions in the field of organ recovery and support.
Conclusion
John O'Neill's contributions to medical technology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in organ transplantation and recovery processes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.