John J O'Shea

Title: The Innovations of John J O'Shea

Introduction

John J O'Shea is a prominent inventor based in Silver Spring, MD (US). He has made significant contributions to the field of immunology and tool design, holding a total of 6 patents. His work has had a profound impact on both scientific research and practical applications.

Latest Patents

Among his latest patents are a snow removal tool and innovations related to Janus family kinases and the identification of immune modulators. One notable patent involves an isolated polynucleotide that encodes the JAK-3 protein. The JAK-3 protein is a protein tyrosine kinase with a molecular weight of approximately 125 kDa, featuring tandem non-identical catalytic domains. It lacks SH2 or SH3 domains and is expressed in natural killer (NK) cells and stimulated or transformed T cells, but not in resting T cells. This protein, along with antibodies to it, is crucial for understanding immune modulation. Furthermore, his methods for identifying therapeutic agents for modulating the immune system utilize these findings.

Career Highlights

John J O'Shea has worked with esteemed organizations such as the National Institutes of Health, a component of the US Department of Health & Human Services, and the United States of America as represented by the Department of Health. His career reflects a commitment to advancing medical science and improving health outcomes.

Collaborations

Throughout his career, O'Shea has collaborated with notable colleagues, including Warren Jaye Leonard and James A Johnston. These partnerships have contributed to the success of his research and innovations.

Conclusion

John J O'Shea's contributions to science and technology exemplify the spirit of innovation. His patents and collaborations have paved the way for advancements in immunology and practical tools, making a lasting impact in his field.