The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2009
Filed:
Aug. 01, 2005
John J. O'shea, Silver Spring, MD (US);
Warren J. Leonard, Bethesda, MD (US);
James A. Johnston, Middletown, MD (US);
Sarah M. Russell, Kensington, MD (US);
Daniel W. Mcvicar, Charles Town, WV (US);
Masaru Kawamura, Rockville, MD (US);
John J. O'Shea, Silver Spring, MD (US);
Warren J. Leonard, Bethesda, MD (US);
James A. Johnston, Middletown, MD (US);
Sarah M. Russell, Kensington, MD (US);
Daniel W. McVicar, Charles Town, WV (US);
Masaru Kawamura, Rockville, MD (US);
Abstract
An isolated polynucleotide encodes JAK-3 protein. JAK-3 protein is a protein tyrosine kinase having a molecular weight of approximately 125 kDa which has tandem non-identical catalytic domains, lacks SH2 or SH3 domains, and is expressed in NK cells and stimulated or transformed T cells, but not in resting T cells. The protein itself and antibodies to this protein are also presented. Further, methods of identifying therapeutic agents for modulating the immune system make use of the foregoing.