Company Filing History:
Years Active: 2006-2011
Title: The Innovations of Daniel W. McVicar
Introduction
Daniel W. McVicar is a prominent inventor based in Charles Town, West Virginia. He has made significant contributions to the field of immunology, particularly through his innovative patents. With a total of 4 patents, McVicar's work has advanced our understanding of immune modulation and therapeutic interventions.
Latest Patents
Among his latest patents, McVicar has developed methods related to Janus family kinases and the identification of immune modulators. One notable patent involves an isolated polynucleotide that encodes the JAK-3 protein. This protein is a protein tyrosine kinase with a molecular weight of approximately 125 kDa, featuring tandem non-identical catalytic domains. It is expressed in natural killer (NK) cells and stimulated or transformed T cells, but not in resting T cells. The patent also includes the protein itself and antibodies to this protein, along with methods for identifying therapeutic agents that can modulate the immune system.
Another significant patent focuses on anti-TREM-like transcript-1 (TLT-1) antibodies and compositions. This invention relates to methods and compositions for modulating platelet activity, as well as treating diseases or disorders associated with platelet activity. The methods involve administering a single chain anti-TREM-like transcript-1 (TLT-1) antibody or a functional fragment or variant thereof in an effective amount to modulate platelet activity.
Career Highlights
Daniel W. McVicar is affiliated with the National Institutes of Health, a component of the U.S. Department of Health & Human Services. His work at this esteemed institution has allowed him to explore groundbreaking research in immunology and contribute to advancements in medical science.
Collaborations
Throughout his career, McVicar has collaborated with notable scientists, including John J. O'Shea and Warren Jaye Leonard. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Daniel W. McVicar's innovative work in the field of immunology has led to significant advancements in understanding immune modulation. His contributions through patents and collaborations continue to influence the scientific community and pave the way for future research.