The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 1994
Filed:
Apr. 06, 1992
Augusto C Ochoa, Washington, DC (US);
Hiromoto Mizoguchi, Frederick, MD (US);
John J O'Shea, Silver Spring, MD (US);
Dan L Longo, Kensington, MD (US);
Cynthia M Loeffler, Bladensburg, MD (US);
The United States of America as represented by the Department of Health, , US;
Regents of the University of Minnesota, Minneapolis, MN (US);
Abstract
A method of determining the level of immunosuppression in a mammal involves determining the level of expression of at least one selected TCR subunit protein, or protein in the T lymphocyte signal transduction pathway, and comparing the level to that found in healthy individuals. The method is useful to identify patients having T lymphocytes capable of activation for autologous adoptive immunotherapy and for identifying agents which cause or reverse immunosuppression.