John Daniel Bailey

Title: John Daniel Bailey: Innovator in Pharmaceutical Chemistry

Introduction

John Daniel Bailey is an accomplished inventor based in Cambridge, MA, with a significant focus on pharmaceutical innovations. With two patents to his name, he has made noteworthy contributions to the field of medicinal chemistry, particularly in developing new compounds capable of treating various cancers.

Latest Patents

Bailey's latest patents include:

1. **Crystalline forms of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one hemihydrate** - This patent focuses on the crystalline forms of Compound 1 and its tautomers. It details processes for preparing these crystalline forms, outlines pharmaceutical compositions that include them, and describes methods for inhibiting a cell division cycle 7 in mammals, with applications in the treatment of cancer mediated by Cdc7.

2. **Process for the synthesis of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one** - This patent presents a novel process for synthesizing this compound, which is identified as a Cdc7 kinase inhibitor. These inhibitors have potential therapeutic applications in managing disordered cell proliferation and treating cancer.

Career Highlights

John Bailey is currently associated with Takeda Pharmaceutical Company Limited, a leading firm in the biotechnology and pharmaceuticals sector. His research and developments focus on harnessing innovative chemical compositions to improve treatment options for cancer patients.

Collaborations

Throughout his career, Bailey has collaborated with esteemed professionals, including Masahiro Mizuno and Kazuhiro Maeda, amplifying the research potential and enhancing the effectiveness of pharmaceutical developments. Their joint efforts have led to advancements in the understanding and treatment of various cancers through innovative medicinal chemistry.

Conclusion

John Daniel Bailey stands out as a notable inventor in the pharmaceutical industry, contributing critical research and innovative patents that address significant health challenges. His work at Takeda Pharmaceutical Company Limited continues to pave the way for advancements in cancer treatments, representing a vital fusion of science and medicine.