The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Apr. 01, 2019
Takeda Pharmaceutical Company Limited, Osaka, JP;
Lei Zhu, Bedford, MA (US);
John Daniel Bailey, Cambridge, MA (US);
Landon Durak, Cambridge, MA (US);
Joshua David Waetzig, Waltham, MA (US);
Masahiro Mizuno, Osaka, JP;
Kazuhiro Maeda, Osaka, JP;
Tsuneo Yasuma, Osaka, JP;
Hiroshi Yamaguchi, Osaka, JP;
Koichiro Fukuoka, Osaka, JP;
Kazuyuki Akiyama, Osaka, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
The present invention provides processes and synthetic intermediates for the synthesis of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4 {3H)-one or a salt, hydrate, or tautomer thereof, or any combination thereof, which are Cdc7 kinase inhibitors, and are useful for the treatment of disorders of cell proliferation, particularly cancer, and other disorders associated with Cdc7 activity.