Downingtown, PA, United States of America

John Curtis Spurlino




Average Co-Inventor Count = 7.8

ph-index = 4

Forward Citations = 29(Granted Patents)


Location History:

  • Dowingtown, PA (US) (2003)
  • Downington, PA (US) (2002 - 2011)
  • Downingtown, PA (US) (2001 - 2014)

Company Filing History:


Years Active: 2001-2014

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8 patents (USPTO):Explore Patents

Title: The Innovative Mind of John Curtis Spurlino

Introduction

John Curtis Spurlino is an accomplished inventor based in Downingtown, PA, with a portfolio of eight notable patents. His work primarily focuses on advancements in medical treatments through innovative methodologies, particularly involving matrix metalloproteinases.

Latest Patents

Spurlino’s recent patents include groundbreaking methods of treatment using allosteric processing inhibitors for matrix metalloproteinases. His inventions feature a crystal structure comprising a complex of the pro form of a matrix metalloproteinase (proMMP) and a small-molecule allosteric processing inhibitor. These inhibitors play a crucial role in halting the activation of proMMP, specifically targeting the activation process of proMMP9. The patents also encompass methods for designing, selecting, and optimizing these small-molecule inhibitors, which are vital for treating diseases linked to improper MMP activity.

Career Highlights

Throughout his career, Spurlino has garnered experience at prominent companies, including Janssen Pharmaceutica and 3-Dimensional Pharmaceuticals, Inc. His work in these organizations has significantly contributed to the development of new therapeutic strategies that leverage the unique properties of matrix metalloproteinases and their inhibitors.

Collaborations

Spurlino has collaborated with notable colleagues such as Aihua Wang and Roger Francis Bone. These partnerships have allowed him to enhance his research capabilities and broaden his impact in the pharmaceutical field, leading to innovative breakthroughs in drug formulations and treatment options.

Conclusion

John Curtis Spurlino stands out as a key figure in the realm of medical innovation. His achievements in patenting methods that address crucial health concerns reflect his dedication to improving patient outcomes through scientific advancements. With a continued focus on matrix metalloproteinases and allosteric inhibitors, Spurlino's work is positioned to inspire future innovations in the medical industry.

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