John A DeMattei

USPTO Granted Patents = 22 (Patent Applications = 6)

Average Co-Inventor Count = 9.1

ph-index = 11

Forward Citations = 639(Granted Patents)

Location History:

San Diego, CO (US) (2011 - 2015)
San Diego, CA (US) (2012 - 2015)
Berthoud, CO (US) (2013 - 2023)

Company Filing History:

8 out of 1,149

Vertex Pharmaceuticals, Inc.

Arena Pharmaceuticals, Inc.

Dynavax Technologies Corporation

where one patent can have more than one assignee

Years Active: 2011-2023

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22 patents (USPTO):Sort by Forward Citations

Abstract keywords

1. 11674163 - Processes for the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof (2023-06-13),

2. 11149292 - Processes for the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof (2021-10-19),

3. 10618896 - Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof (2020-04-14),

4. 9751839 - Process for making modulators of cystic fibrosis transmembrane conductance regulator (2017-09-05),

5. 9562017 - Hydrogen sulfate salt (2017-02-07),

6. 9447041 - Processes for the preparation of (R)-2-(7-4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof (2016-09-20),

7. 9371287 - Process for making modulators of cystic fibrosis transmembrane conductance regulator (2016-06-21),

8. 9175320 - Processes for the preparation of (R)-2-(7-4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof (2015-11-03),

9. 9156795 - Hydrogen sulfate salt (2015-10-13),

10. 9024040 - Processes for preparing benzimidazole compounds (2015-05-05),

11. 8952197 - [object Object] (2015-02-10),

12. 8853419 - [object Object] (2014-10-07),

13. 8835639 - Process for making modulators of cystic fibrosis transmembrane conductance regulator (2014-09-16),

14. 8765957 - Process for making modulators of cystic fibrosis transmembrane conductance regulator (2014-07-01),

15. 8623894 - Solid forms of N-[2,4-Bis(1,1-dimethyethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquioline-3-carboxamide (2014-01-07),

Title: Innovations of John A DeMattei: A Pioneer in Biopharmaceutical Patents

Introduction

John A DeMattei is an accomplished inventor based in Berthoud, Colorado, known for his significant contributions to the field of biopharmaceuticals. With a portfolio of 22 patents, his innovative work has focused primarily on the development of compounds relevant to treating various medical conditions, particularly those associated with the immune system and inflammation.

Latest Patents

Among his most recent patents are innovative processes for the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and its salts. This compound is an S1P1 receptor modulator, demonstrating therapeutic potential in treating S1P1 receptor-associated disorders, including autoimmune diseases, transplant rejection, inflammatory conditions, and cancer. His inventions showcase pathways for developing intermediates that enhance the accessibility and utility of this crucial compound in medical applications.

Career Highlights

DeMattei has made considerable strides in the biopharmaceutical industry, having worked with prominent companies such as Vertex Pharmaceuticals and Array Biopharma. His career is characterized by a commitment to research and development, leading to innovative solutions that contribute positively to the healthcare sector. His inventions have positioned him as a key figure in the advancement of treatments for complex disorders.

Collaborations

Collaboration has been an essential aspect of DeMattei's success. He has worked closely with talented colleagues like Adam R Looker and Stefanie Roeper, contributing to shared projects that explore new therapeutic avenues. These partnerships have not only enhanced his work but have also fostered an environment of innovation where groundbreaking ideas can thrive.

Conclusion

John A DeMattei's innovative contributions within the biopharmaceutical field underscore the importance of research in developing effective treatments. His array of patents reflects his dedication to improving healthcare through scientific advancements. As he continues to push the boundaries of innovation, the impact of his work is sure to be felt across the medical community and beyond.

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6 patents pending:

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