Jiro Shimada

Title: **The Innovative Mind of Jiro Shimada**

Introduction

Jiro Shimada, based in Tokyo, Japan, is a notable inventor with a remarkable portfolio that includes three patents. His work has significantly contributed to the fields of proteome analysis and enzymatic modifications, demonstrating a deep understanding of molecular biology and biochemistry.

Latest Patents

Shimada's latest innovations focus on two groundbreaking patents. The first is a **Proteome Analysis Method and Proteome Analysis System**. This method involves the use of a tandem type mass spectrometer to calculate bond dissociation energy through molecular simulation, enabling the prediction of cleavage patterns of peptides, peak positions in mass spectra, and intensity ratios. Utilizing this prediction along with experimental information allows for the precise identification of proteins, showcasing a sophisticated approach to proteomics.

The second patent details a **Method of Altering Enzymes and a Novel Neopullulanase**. In this invention, an enzyme's efficiency is improved by introducing an additional hydrophobic group, which enhances the hydrophobic environment and minimizes water molecule interference. The selection of the modification site and the type of hydrophobic group is guided by an in-depth analysis of the target enzyme’s amino acid sequence, three-dimensional structure, and reaction mechanism. This innovative method led to the successful substitution of an amino acid residue in neopullulanase derived from Bacillus stearothermophilus.

Career Highlights

Throughout his illustrious career, Jiro Shimada has worked with prominent organizations, including NEC Corporation and Nippon Electric Co., Ltd. These experiences provided him with a platform to apply his inventive skills in practical settings, contributing to advancements in technology and science.

Collaborations

Jiro Shimada has collaborated with esteemed colleagues such as Yoichi Miyagawa and Hiroshi Iguchi. Their combined expertise has undoubtedly enriched Shimada's projects, fostering an environment of innovation and knowledge sharing.

Conclusion

Jiro Shimada stands out as a pivotal figure in the realm of scientific innovation. With his advanced patents in proteome analysis and enzyme modifications, he continues to make significant strides in biotechnology. His collaborative efforts and professional background reflect a commitment to enhancing scientific understanding and developing practical applications that can benefit various industries.