Nec Corporation

Nippon Electric Co., Ltd.

Ezaki Glico Kabushiki Kaisha

Jiro Shimada

Minoru Asogawa

Shigetaka Okada

Michiyo Yanase

Hiroki Takata

Takashi Kuriki

Toshimasa Yamazaki

Toshikazu Takada

Kenichi Kamijyo

Hiroshi Iguchi

Kenichiro Tsuda

Yoichi Miyagawa

A proteome analysis method includes using a tandem type mass spectrometer to calculate bond dissociation energy by using molecular simulation, using the bond dissociation energy to obtain prediction information including a cleavage pattern of a peptide and/or peak positions in a mass spectrum and/or the intensity ratio of the mass spectrum, and identifying a protein by using the prediction information and experiment information.

Proteome analysis method and proteome analysis system

An enzyme is altered by introducing an additional hydrophobic group to enhance the hydrophobic environment in the enzyme so as to interfere with entrance of a water molecule. In this connection, the site of introduction and kind of hydrophobic group to be introduced are selected on the basis of comprehensive analysis of amino acid sequence, three-dimensional structure, reaction mechanism or the like of the target enzyme. Using this method, an amino acid residue of neopullulanase derived from Bacillus stearothermophilus was replaced by another amino acid.

Method of altering enzymes and a novel neopullulanase

A low-power consumption, high-speed electronic switching system has a pair of complementary switching means connected between opposite polarity terminals of the voltage source and an output terminal. The pair of switches provides a variable impedance for applying one or the other of the polarities and said output terminal. To speed an appearance of that polarity, an inverter is coupled between an input and an output terminal via a differentiating capacitor. The differentiated inverter output speeds the appearance of the switched output signal during the interval before the complementary input becomes effective thereat.

Low power consumption high speed transistor circuit comprising a

Growing community of inventors

Tokyo, Japan

Jiro Shimada