Company Filing History:
Years Active: 2023
Title: Innovations by Jinqiang Wang in Glucose-Responsive Insulin Delivery
Introduction
Jinqiang Wang, an innovative inventor based in Raleigh, NC, has made significant contributions to the field of diabetes treatment through his research and development of novel insulin delivery systems. With a total of four patents to his name, Wang's work focuses on leveraging advanced polymeric materials for enhanced drug delivery mechanisms.
Latest Patents
Two of Wang’s latest patents highlight his pioneering approach to glucose-responsive insulin delivery systems. The first, titled "Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response," introduces a composition that includes a glucose-responsive charge-switchable polymer. This innovative polymer can complex with negatively charged therapeutic agents, such as insulin, under normoglycemic conditions. Once glucose levels rise, the polymer's positive charge is diminished, leading to the disassembly of the polymer/therapeutic agent complex and allowing for rapid insulin release. Additionally, this patent describes various pharmaceutical compositions, nanoparticles, microneedle arrays containing the polymer, and methods for treating diabetes.
The second patent, "Glucose transporter inhibitor-modified insulin for glucose-responsive insulin delivery," describes an insulin delivery system that utilizes the interaction between glucose-modified insulin and glucose transporters present on red blood cells (RBCs). By conjugating insulin with a competitive inhibitor of glucose transporters, the system can efficiently bind insulin to RBC membranes. This binding proves to be reversible under hyperglycemic conditions, enabling a swift release of insulin that subsequently lowers blood glucose levels in vivo.
Career Highlights
Wang’s career has been marked by significant advancements in biomedical engineering, particularly in diabetes management technologies. His research at North Carolina State University showcases his dedication to developing effective solutions for improving the lives of individuals dealing with diabetes.
Collaborations
Jinqiang Wang has collaborated closely with esteemed colleagues, including Zhen Gu and Yanqi Ye, contributing to a dynamic research environment that enhances innovation and exploration in the fields of biomedical devices and drug delivery systems.
Conclusion
In summary, Jinqiang Wang stands out as a noteworthy inventor whose work in glucose-responsive insulin delivery systems reflects a deep understanding of material science and pharmacology. His contributions have the potential to revolutionize diabetes treatment, making it more efficient and responsive to patients’ needs. Wang's patents exemplify the kind of innovation that is crucial for addressing complex health challenges, and his work continues to inspire future developments in the field.