Company Filing History:
2 out of 4 
1 out of 3 Years Active: 2018-2024
Title: Innovations in Pluripotent Stem Cell Research by Jingyang Guan
Introduction
Jingyang Guan is a prominent inventor based in Beijing, China, known for her significant contributions to the field of stem cell research. With a focus on reprogramming non-pluripotent cells into pluripotent stem cells, she has developed innovative methods that hold great potential for medical applications.
Latest Patents
Jingyang Guan holds two notable patents. The first patent is titled "Methods for reprogramming non-pluripotent cells into pluripotent stem cells." This invention provides chemical inducers of pluripotency (CIP), which include glycogen synthase kinase inhibitors, TGFβ receptor inhibitors, cyclic AMP agonists, and S-adenosylhomocysteine hydrolase (SAH) inhibitors or histone acetylators. The method involves contacting a cell with these CIPs for a sufficient period to reprogram the cell into a pluripotent stem cell with embryonic stem cell-like characteristics (CiPSC). The isolated chemically induced pluripotent stem cells (CiPSCs) and their progeny can be utilized in various applications, including cell therapy and tissue engineering.
The second patent is titled "Compositions and methods for reprogramming non-pluripotent cells into pluripotent stem cells." This invention outlines a composition and method for inducing pluripotency in non-pluripotent eukaryotic cells. The composition comprises CIPs, including glycogen synthase kinase (GSK) inhibitors, TGFβ receptor inhibitors, cyclic AMP agonists, and SAH inhibitors, along with an optional agent that promotes histone acetylation. The method involves contacting a cell with these CIPs for a sufficient period to achieve reprogramming into a pluripotent stem cell.
Career Highlights
Throughout her career, Jingyang Guan has worked with various organizations, including Hong Guan Ltd. and Beihao Stem Cell and Regenerative Medicine Research Institute Co., Ltd. Her work has significantly advanced the understanding and application of stem cell technology.
Collaborations
Jingyang has collaborated with notable colleagues in her field, including Hongkui Deng and Yang Zhao, who have contributed to her research endeavors.
Conclusion
Jingyang Guan's innovative work in the field of pluripotent stem cells showcases her dedication to advancing medical science
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