Company Filing History:
7 out of 17 
2 out of 5,175 
Years Active: 2013-2017
Title: Innovations of Jinfang Liao in Fluorescent Calcium Ion Indicators
Introduction
Jinfang Liao is a prominent inventor based in Foster City, CA, known for his significant contributions to the field of fluorescent calcium ion indicators. With a total of eight patents to his name, Liao has made remarkable advancements in the detection and quantification of metal ions, particularly calcium ions.
Latest Patents
One of Liao's latest patents is focused on fluorogenic calcium ion indicators and methods of using them. This patent provides fluorogenic compounds that are useful for preparing fluorescent calcium ion indicators. The fluorescent indicators are designed for the detection, discrimination, and quantification of metal ions. The compounds include a chelating group based on a 2-aminophenoxyethylene glycol 2-aminoethyl ether, N,N,N',N'-tetraacetic acid (PEGTA) moiety, or a precursor thereof. The phenyl group of the PEGTA is substituted with or fused with a fluorophore moiety of interest. These methods are particularly useful in detecting intracellular calcium ions. Additionally, Liao has developed carbofluorescein lactone ion indicators and their applications, which are fluorescent dyes useful for preparing fluorescent metal ion indicators.
Career Highlights
Throughout his career, Jinfang Liao has worked with notable companies such as Aat Bioquest, Inc. and Becton Dickinson and Company Limited. His work has significantly impacted the field of fluorescent indicators, enhancing the capabilities of researchers and scientists in various applications.
Collaborations
Liao has collaborated with several professionals in his field, including Zhenjun Diwu and Haitao Guo. These collaborations have contributed to the advancement of his research and the development of innovative solutions in the detection of metal ions.
Conclusion
Jinfang Liao's contributions to the field of fluorescent calcium ion indicators demonstrate his innovative spirit and dedication to advancing scientific research. His patents and collaborations continue to influence the way researchers detect and quantify metal ions, showcasing the importance of his work in the scientific community.
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