Location History:
- Hsinchu, TW (2002 - 2014)
- Hsinchu, CN (2015)
Company Filing History:
5 out of 3,682 
2 out of 618 Years Active: 2002-2015
Title: Innovations and Contributions of Inventor Jih Ru Hwu
Introduction
Jih Ru Hwu is a prominent inventor based in Hsinchu, Taiwan. He has made significant contributions to the field of chemistry, particularly in the development of novel compounds for cancer treatment. With a total of seven patents to his name, Hwu's work focuses on creating effective therapeutic agents that target hypoxic cells.
Latest Patents
Among his latest patents, Hwu has developed conjugates of nitroimidazoles that serve as chemotherapeutic agents. These novel compounds are derivatives of tetra-O-methyl nordihydroguaiaretic acid (NDGA) and include pharmaceutically acceptable salts, solvates, and stereoisomers. The NDGA derivatives possess a nitroimidazole moiety, which demonstrates preferential toxicity to hypoxic cells, making them effective anti-cancer drugs. This is particularly important as hypoxic cells are often more resistant to conventional anti-cancer treatments. Additionally, Hwu has patented a phosphate-containing nanoparticle delivery vehicle that enhances the hydrophilicity of active ingredients and targets tumor cells specifically. This innovative delivery system offers advantages such as biocompatibility, magnetism, and controllable drug release.
Career Highlights
Hwu has held positions at prestigious institutions, including The Johns Hopkins University and National Cheng Kung University. His work in these environments has allowed him to collaborate with leading researchers and contribute to groundbreaking advancements in cancer therapy.
Collaborations
Some of Hwu's notable coworkers include Ru Chih C Huang and Jonathan Daniel Heller. Their collaborative efforts have furthered the research and development of innovative therapeutic solutions.
Conclusion
Jih Ru Hwu's contributions to the field of chemistry and cancer treatment through his patents and collaborations highlight his role as a significant inventor. His innovative approaches to targeting hypoxic cells and developing effective drug delivery systems continue to impact the medical field positively.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.